Dimeric 1,4-benzoquinone derivatives and a resorcinol derivative from Ardisia gigantifolia.

نویسندگان

  • Hongwei Liu
  • Feng Zhao
  • Ruiyun Yang
  • Manyuan Wang
  • Meiqing Zheng
  • Yisong Zhao
  • Xue Zhang
  • Feng Qiu
  • Hengshan Wang
چکیده

Naturally occurring dimeric 1,4-benzoquinone derivatives, belamcandaquinones F, G, H, and I, as well as one resorcinol derivative and four known compounds, were isolated from rhizomes of Ardisia gigantifolia. Their structures were established by means of spectroscopic analyses. All compounds were tested against cell lines PC-3, EMT6, A549, Hela, RM-1, and SGC7901 for cytotoxicity in vitro. In comparison with cisplatin, compounds 5 and 6 showed a strong cytotoxicity with IC(50) values less than 30 microM for most cell lines tested.

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عنوان ژورنال:
  • Phytochemistry

دوره 70 6  شماره 

صفحات  -

تاریخ انتشار 2009